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Wellcome Trust has launched a new funding call to establish global infrastructure hubs that will enable more timely, relevant, and affordable AI-enabled evidence synthesis to address policy-scale challenges in global health. This initiative is part of Wellcome’s first series of Evidence Synthesis Infrastructure Collaborative investments and aims to establish foundational evidence synthesis capabilities that can be used to address Wellcome’s strategic priorities in global health, strengthen production, use and dissemination of evidence synthesis, enable AI-enabled approaches, and build infrastructure that supports timely and policy-relevant decision-making. Wellcome plans to fund five new global infrastructure hubs through this competitive call. Each award will range from £1.5 million to £1.9 million, with a funding duration of three to five years. The hubs are expected to build sustainable infrastructure that strengthens evidence synthesis capacity in low- and middle-income countries and supports policy-scale responses to global health challenges. Teams of researchers, whether newly formed or existing, are eligible to apply if they demonstrate expertise in evidence synthesis production, use, and dissemination. The lead applicant must be based in a low- and middle-income country, and the administering organisation must also be located in a low- and middle-income country, excluding mainland China. Eligible administering organisations include higher education institutions, research institutes, healthcare organisations, and not-for-profit or non-governmental research organisations. While commercial organisations cannot serve as administering organisations, co-applicants and collaborators may be affiliated with them. Applications are encouraged from teams that bring diverse expertise and interdisciplinary perspectives, including researchers at different career stages from early-career to experienced professionals. Certain restrictions apply to this call. Applicants must not propose activities involving the transfer of funds into mainland China. Individuals may serve as lead applicant on only one application and co-applicant on another, or as co-applicant on two applications, provided the projects are distinct and there is no overlap in activities. Applicants must demonstrate sufficient capacity to manage multiple funded projects if applicable and must not exceed the maximum number of Wellcome awards. Members of the ESIC Steering Group are not eligible to apply. Through this investment, Wellcome aims to strengthen evidence synthesis infrastructure and support research communities in low- and middle-income countries to deliver high-quality, AI-enabled evidence that can inform policy and improve global health outcomes.
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